Zollinger-Ellison Syndrome (ZES) FAQ
What causes Zollinger-Ellison Syndrome?
It's caused by gastrinomas, tumors that produce excess gastrin, leading to high stomach acid.
What are common symptoms of ZES?
Severe ulcers, diarrhea, abdominal pain, and nausea are typical symptoms.
How is Zollinger-Ellison Syndrome diagnosed?
Blood tests for gastrin levels, endoscopy, and imaging tests to locate tumors.
Can ZES be cured?
Possibly if the tumor is removed; otherwise, managed with medication.
What medications treat ZES?
Proton pump inhibitors (PPIs) like Pantoprazole and Omeprazole.
Is surgery an option for ZES?
Yes, if the gastrinoma can be localized and removed.
How often do gastrinomas metastasize?
About 90% are malignant, but many grow slowly.
Can diet help manage ZES symptoms?
Avoiding spicy, acidic foods may help, but medication is primary.
What complications arise from untreated ZES?
Life-threatening ulcer bleeding or perforation.
How frequently should ZES patients follow up?
Regularly, every 3-6 months, to monitor tumor growth and adjust treatment.
Can ZES affect children?
Rarely, typically diagnosed in adults.
What role does genetic testing play in ZES?
For familial cases, as part of Multiple Endocrine Neoplasia type 1.
How is Octreotide used in ZES treatment?
To control tumor growth and reduce gastrin secretion in some cases.
Are there clinical trials for ZES in Malaysia?
Availability varies; consult a specialist for current options.
Can ZES lead to other health issues?
Yes, including malnutrition from chronic diarrhea and ulcers.
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