Systemic Mastocytosis FAQ
What causes systemic mastocytosis?
The exact cause is unknown, but it involves a somatic mutation in the KIT gene, leading to uncontrolled mast cell growth.
Is systemic mastocytosis cancer?
It's a rare blood disorder that can have cancer-like features in aggressive forms, but not all types are considered cancer.
What are common symptoms of systemic mastocytosis?
Frequent allergic reactions, skin lesions, abdominal pain, diarrhea, fatigue, and in severe cases, anaphylaxis.
How is systemic mastocytosis diagnosed in Malaysia?
Through a combination of blood tests, bone marrow biopsy, and genetic testing, typically at specialized hospitals.
Can systemic mastocytosis be cured?
Currently, there's no known cure, but symptoms can be managed, and progression slowed with medication.
What medications treat systemic mastocytosis?
Imatinib, midostaurin, antihistamines, and mast cell stabilizers like ketotifen are commonly used.
Is systemic mastocytosis life-threatening?
Severe forms can be life-threatening due to anaphylaxis risk or organ damage if untreated.
How rare is systemic mastocytosis?
It affects fewer than 1 in 100,000 people, making it an orphan disease with limited awareness.
Can children develop systemic mastocytosis?
Yes, though it's more common in adults. Pediatric cases often have a better prognosis.
What triggers mast cell activation in this condition?
Triggers vary but can include stress, temperature changes, certain foods, or medications.
How does systemic mastocytosis affect the skin?
It can cause urticaria pigmentosa, characterized by itchy, red, or brown skin spots.
Are there support groups for systemic mastocytosis in Malaysia?
Yes, rare disease support groups and online forums offer community and resources.
Can diet help manage systemic mastocytosis?
A low-histamine diet may help alleviate some symptoms, under guidance from a healthcare provider.
What is the prognosis for systemic mastocytosis?
Varies by type; indolent forms have a better outlook, while aggressive types require prompt treatment.
Is systemic mastocytosis contagious?
No, it's not contagious; the cause is related to genetic mutations, not infection.
Releated topics
- Can aspiration pneumonia cause long-term lung damage?
- Can Barrett's Esophagus be reversed?
- Can duodenal ulcers be transmitted?
- How does H. pylori infection impact prophylaxis?
- How often should I follow up with my doctor after diagnosis?
- Is surgery ever required for gastritis?
- What medications are commonly prescribed for GERD in Malaysia?
- What causes H. pylori infection?
- How is hiatal hernia diagnosed in Malaysia?
- What is Laryngopharyngeal Reflux?