Primary Biliary Cholangitis is a chronic liver disease characterized by the progressive destruction of bile ducts within the liver, leading to cholestasis and potential liver failure. Early diagnosis and treatment are crucial for managing symptoms and slowing disease progression.

Primary Biliary Cholangitis (PBC) FAQ


What causes Primary Biliary Cholangitis?

The exact cause is unknown, but it involves an abnormal immune response targeting bile ducts.

Is PBC contagious?

No, Primary Biliary Cholangitis is not contagious.

What are common symptoms of PBC?

Early symptoms may include fatigue and itching. Advanced stages can lead to jaundice and abdominal pain.

How is PBC diagnosed?

Diagnosis involves blood tests (e.g., ALP, AMA), liver imaging, and sometimes liver biopsy.

Is there a cure for Primary Biliary Cholangitis?

Currently, no cure exists, but treatments can manage symptoms and slow progression.

What is the main treatment for PBC?

Ursodeoxycholic Acid is the first-line treatment to reduce liver damage.

Can lifestyle changes help manage PBC?

Maintaining a healthy diet, avoiding alcohol, and regular exercise may help.

How often should PBC patients see a doctor?

Regular follow-ups (every 3-6 months) are recommended to monitor liver function.

Can PBC lead to liver transplant?

In advanced cases, liver transplantation may be necessary.

Are there any new treatments for PBC?

Research is ongoing, with obeticholic acid being a recent addition to treatment options.

Can PBC affect other parts of the body?

Some patients may experience symptoms like dry eyes or mouth due to associated autoimmune conditions.

Is PBC more common in women?

Yes, PBC predominantly affects women, typically between 30-50 years old.

Can PBC be inherited?

Genetic factors may contribute to susceptibility, but it's not directly inherited.

Pacing activities, prioritizing rest, and addressing underlying anemia can help manage fatigue.

Are there any dietary restrictions for PBC patients?

A balanced diet low in fat and high in fiber is recommended, with possible vitamin D and calcium supplementation.

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