Pemphigus is a rare, chronic autoimmune skin disorder characterized by blistering of the skin and mucous membranes due to autoantibodies targeting desmoglein proteins, leading to skin cell separation.

Pemphigus Vulgaris FAQ


What triggers Pemphigus flare-ups?

Flare-ups can be triggered by UV radiation, stress, infections, or certain medications.

Is Pemphigus contagious?

No, Pemphigus is not contagious; it's an autoimmune disorder.

How is Pemphigus diagnosed in Malaysia?

Diagnosis involves skin biopsy, blood tests for autoantibodies, and clinical evaluation.

Can Pemphigus be cured?

Currently, there's no cure, but symptoms can be managed with medication.

What are common Pemphigus symptoms?

Painful blisters on skin and mucous membranes, itching, and skin lesions.

How do doctors treat mild Pemphigus cases?

Mild cases may be treated with topical corticosteroids and immunosuppressants.

What is the role of immunosuppressants in treatment?

They reduce immune system activity to decrease antibody production.

Can Pemphigus affect the eyes?

Yes, ocular involvement can occur, requiring prompt medical attention.

How long does a Pemphigus flare-up typically last?

Duration varies; with treatment, flare-ups can resolve within weeks to months.

Is sun protection important for Pemphigus patients?

Yes, UV protection is crucial to prevent trigger-induced flare-ups.

Can diet influence Pemphigus management?

While diet doesn't cause Pemphigus, a balanced diet aids overall health and healing.

What role does rituximab play in treatment?

Rituximab, a biologic, targets B-cells to reduce autoantibody production.

How often are follow-ups needed for Pemphigus patients?

Regular follow-ups are necessary to adjust treatment and monitor side effects.

Can Pemphigus affect mucous membranes in the mouth?

Yes, oral mucosa involvement is common, causing painful sores and difficulty eating.

Are there any Pemphigus support groups in Malaysia?

Yes, organizations like the Malaysian Society of Dermatology offer support and resources.

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