A medical regimen designed to prevent the immune system from attacking a transplanted organ, typically involving immunosuppressive medications to reduce rejection risk and ensure graft survival.

Post-Transplant Immunoprophylaxis for Rejection FAQ


What is rejection prophylaxis after an organ transplant?

It's a treatment plan using medications to prevent the immune system from rejecting the new organ.

Why is immunosuppression crucial post-transplant?

To suppress the immune system's natural response to attack foreign tissue, ensuring the graft's survival.

What medications are commonly used?

Tacrolimus, Cyclosporine, Mycophenolate Mofetil, Sirolimus, and Prednisone are standard.

How long must immunosuppressants be taken?

Typically, for the lifespan of the graft; stopping can lead to rejection.

What are common side effects of these medications?

Increased infection risk, hypertension, diabetes, and kidney dysfunction.

Can I lead a normal life post-transplant?

Yes, with proper medication adherence and lifestyle adjustments.

How often are follow-up visits needed?

Frequent initially, then regular check-ups to monitor graft function and adjust medications.

Can I travel after an organ transplant?

Yes, but ensure access to medical care and carry a travel health letter.

What vaccines can I receive?

Inactivated vaccines are safe; avoid live vaccines due to immunosuppression.

Can I consume alcohol?

Limit or avoid alcohol to prevent medication interactions and liver damage.

How does diet affect transplant health?

A balanced, low-salt diet helps manage blood pressure and reduces drug side effects.

What are rejection symptoms?

Fever, fatigue, swelling, decreased urine output, or graft area pain.

Is rejection always preventable?

Not entirely, but prophylaxis significantly reduces the risk.

Can I switch medications?

Only under medical supervision, as this requires careful monitoring.

What if I miss a dose?

Take it as soon as remembered, but never double the dose.

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