Post-Transplant Immunosuppressive Therapy Failure (Rejection) FAQ
What causes organ transplant rejection?
Rejection occurs when the immune system identifies the transplanted organ as foreign and attacks it.
What are symptoms of acute rejection?
Fever, fatigue, organ dysfunction (e.g., reduced urine output for kidney transplants), and swelling or tenderness.
How is organ rejection diagnosed?
Through blood tests, imaging studies, and biopsy of the transplanted organ.
Can rejection be treated?
Yes, typically by adjusting immunosuppressive medications or administering high-dose steroids.
What is the role of immunosuppressants?
They suppress the immune system to prevent it from attacking the transplanted organ.
Are immunosuppressants lifelong?
Usually, yes, to maintain organ function and prevent chronic rejection.
What increases rejection risk?
Non-adherence to medication, infection, or an overactive immune response.
How often do transplanted organs fail?
Rates vary by organ type; approximately 20-40% of kidneys fail within 10 years.
Is rejection more common in certain organs?
Lung and pancreas transplants have higher rejection rates compared to kidney transplants.
Can a second transplant be done after rejection?
Possibly, but outcomes may be poorer due to sensitization.
What lifestyle changes help prevent rejection?
Adhere strictly to medication regimens, maintain a healthy diet, and avoid infections.
How does smoking affect transplant success?
Smoking increases rejection risk and reduces overall transplant survival rates.
Are vaccines safe post-transplant?
Inactivated vaccines are generally safe; live vaccines should be avoided.
Can I travel to Malaysia for a transplant?
Yes, medical tourism is feasible, but ensure continuity of post-transplant care.
What support is available in Malaysia for transplant patients?
Public and private hospitals offer transplant services, with support groups available.
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