Lupus nephritis is a kidney inflammation caused by systemic lupus erythematosus (SLE), an autoimmune disease. It occurs when the immune system mistakenly attacks kidney tissues, leading to swelling, blood in urine, and potential kidney damage.

Lupus Nephritis FAQ


What causes lupus nephritis?

It's caused by a misdirected immune response in SLE patients, targeting kidney tissues.

What are common symptoms of lupus nephritis?

Swelling (edema), blood in urine (hematuria), proteinuria, and high blood pressure.

How is lupus nephritis diagnosed?

Through urine tests, blood tests, and a kidney biopsy to assess damage extent.

Can lupus nephritis be cured?

While not curable, early treatment can manage symptoms and prevent progression.

What medications treat lupus nephritis?

Corticosteroids, immunosuppressants like mycophenolate mofetil, and biologics.

Is dialysis required for lupus nephritis?

Only in severe, advanced cases where kidneys fail; early treatment aims to prevent this.

How does diet affect lupus nephritis?

Reducing salt, protein, and potassium intake can help manage symptoms and kidney function.

Can lupus nephritis recur after treatment?

Yes, relapse is possible, requiring ongoing monitoring and medication adjustments.

What role do immunosuppressants play?

They suppress the overactive immune system to prevent further kidney damage.

How often are follow-up appointments needed?

Regularly, ideally every 3-6 months, to monitor kidney function and treatment efficacy.

Can lupus nephritis affect pregnancy?

Yes, it can increase risks; pre-pregnancy planning with a healthcare provider is crucial.

What are the stages of lupus nephritis?

Classified into six classes (I-VI) based on biopsy findings, guiding treatment decisions.

Is lupus nephritis always associated with SLE?

Yes, it's a complication of SLE; not everyone with SLE develops nephritis.

How long does treatment typically last?

Varies by individual; some may require long-term or lifelong medication.

Can lifestyle changes impact lupus nephritis?

Yes, maintaining a healthy weight, quitting smoking, and managing stress can help.

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