Granulomatosis with Polyangiitis (previously Wegener's Granulomatosis) FAQ
What causes Granulomatosis with Polyangiitis?
The exact cause of GPA is unknown, but it involves an abnormal immune response, potentially triggered by environmental factors.
What are common symptoms of GPA?
Nasal congestion, sinusitis, cough, shortness of breath, kidney issues, and skin lesions.
How is GPA diagnosed?
Through blood tests, imaging (CT scans), and biopsy of affected tissues to detect vasculitis and granulomas.
Is GPA treatable?
Yes, with immunosuppressive medications and corticosteroids to manage inflammation and prevent organ damage.
Can GPA recur after treatment?
Yes, relapse is possible, requiring ongoing monitoring and medication adjustments.
What role does Rituximab play in GPA treatment?
Rituximab helps reduce B-cell activity, decreasing inflammation and the risk of relapse.
Are there lifestyle changes to manage GPA?
Maintaining a healthy diet, avoiding infections, and managing stress are beneficial.
Can GPA affect the kidneys?
Yes, kidney involvement is common, emphasizing the need for early treatment to prevent failure.
How long does GPA treatment typically last?
Treatment duration varies, often involving long-term immunosuppression to prevent relapse.
Is GPA contagious?
No, GPA is an autoimmune disease and cannot be transmitted to others.
What is the prognosis with timely treatment?
Most patients experience significant improvement and can lead active lives with proper management.
Are there specific tests for GPA in Malaysia?
Yes, healthcare providers in Malaysia use standardized diagnostic protocols, including ANCA tests.
Can GPA be mistaken for other conditions?
Yes, GPA can resemble infections or other autoimmune diseases, requiring careful diagnosis.
What is the role of Methotrexate in GPA treatment?
Methotrexate is used as a steroid-sparing agent and to maintain remission.
Are there support groups for GPA patients in Malaysia?
Yes, several patient support groups and online forums offer guidance and community.
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