Familial Mediterranean Fever is an inherited inflammatory disorder characterized by recurrent episodes of fever and painful inflammation, often affecting the abdomen, chest, or joints. Common in Mediterranean populations, it's caused by mutations in the MEFV gene.

Familial Mediterranean Fever (FMF) FAQ


What causes Familial Mediterranean Fever?

FMF is caused by mutations in the MEFV gene, leading to abnormal protein production and uncontrolled inflammation.

Who is most likely to get FMF?

Individuals of Mediterranean descent, including Turks, Arabs, and Ashkenazi Jews, are at higher risk.

What are common FMF symptoms?

Recurring fever, abdominal pain, chest pain, joint pain, and skin rash.

How is FMF diagnosed?

Through genetic testing, medical history, and physical examination to rule out other conditions.

Is FMF contagious?

No, it's an inherited genetic disorder, not caused by infections.

What medications treat FMF?

Colchicine is commonly prescribed to prevent attacks and reduce inflammation.

Can FMF be cured?

While there's no cure, symptoms can be effectively managed with medication.

How often do FMF attacks occur?

Frequency varies; some experience attacks weekly, others monthly or less.

What triggers FMF attacks?

Triggers are not fully understood but may include stress, physical exertion, or infections.

Can FMF lead to complications?

Untreated, it can cause amyloidosis, a serious kidney condition.

How is FMF managed in Malaysia?

Through specialist care, genetic counseling, and access to prescribed medications like colchicine.

Is colchicine available in Malaysia?

Yes, it's available by prescription from healthcare providers.

Can lifestyle changes help manage FMF?

Maintaining a healthy lifestyle can help reduce attack frequency and severity.

Are there support groups for FMF in Malaysia?

Check with local patient organizations or online communities for support and resources.

How does FMF affect daily life?

Attacks can disrupt daily activities, but with proper management, many lead normal lives.

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