Colchicum Autumnale (Autumn Crocus) FAQ
What is Colchicum Autumnale used for in Malaysia?
Primarily treats gout and familial Mediterranean fever by reducing inflammation.
How does Colchicum Autumnale work?
Inhibits microtubule formation, decreasing white blood cell migration to inflamed areas.
Is Colchicum Autumnale available over-the-counter in Malaysia?
Generally requires a prescription due to toxicity risks and dosage sensitivity.
What are common side effects of Colchicum Autumnale?
Nausea, vomiting, diarrhea, and abdominal pain, especially with high doses.
Can Colchicum Autumnale prevent gout attacks?
No, it's used to treat acute attacks, not prevent them; prophylactic use is uncommon.
How is Colchicum Autumnale administered?
Orally (tablets) or via injection, with oral being more common for gout treatment.
What is the typical dosage for gout?
Varies by patient; initial dose often 1.2 mg, followed by .6 mg one hour later.
Are there drug interactions with Colchicum Autumnale?
Yes, interacts with CYP3A4 inhibitors (e.g., clarithromycin), increasing toxicity risk.
Is Colchicum Autumnale safe during pregnancy?
Category D in many regions; potential fetal risks, use only if benefits outweigh risks.
Can lifestyle changes enhance Colchicum Autumnale's effectiveness?
Yes, maintaining a low-purine diet and hydration can complement treatment.
What if I miss a dose of Colchicum Autumnale?
Take as soon as remembered, but skip if near the next dose to avoid overdose.
How long does Colchicum Autumnale take to work?
Typically reduces gout symptoms within 24-48 hours of initial treatment.
Are natural alternatives to Colchicum Autumnale available in Malaysia?
Some herbal supplements claim benefits, but efficacy and safety are often unproven.
What serious conditions can arise from Colchicum Autumnale overdose?
Severe gastrointestinal symptoms, bone marrow suppression, and even death.
Does Colchicum Autumnale treat other conditions besides gout?
Also used for familial Mediterranean fever; other uses are less common and evidence-based.
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