Pseudomembranous Colitis (Clostridioides difficile Infection) FAQ
What causes pseudomembranous colitis?
It's primarily caused by Clostridioides difficile (C. diff) infection, often after antibiotic use disrupts normal gut flora.
What are common symptoms of pseudomembranous colitis?
Diarrhea, abdominal pain, fever, and in severe cases, blood in stool or dehydration.
How is pseudomembranous colitis diagnosed?
Through stool tests to detect C. diff toxins, and sometimes colonoscopy to visualize pseudomembranes.
What is the primary treatment for pseudomembranous colitis?
Antibiotics like vancomycin or fidaxomicin to target C. diff, with metronidazole as an alternative in mild cases.
Can probiotics help with pseudomembranous colitis?
Certain probiotics may help restore gut flora, but evidence is mixed; consult a doctor for guidance.
How long does recovery from pseudomembranous colitis take?
Most recover within 1-2 weeks with treatment, but severe cases may require hospitalization.
Can pseudomembranous colitis recur after treatment?
Yes, recurrence is common; preventing further antibiotic exposure reduces risk.
What dietary changes help manage pseudomembranous colitis?
A bland diet, avoiding spicy or fatty foods, and adequate hydration are recommended.
Is pseudomembranous colitis contagious?
C. diff spores can spread through contact with contaminated surfaces or healthcare settings.
How can I prevent pseudomembranous colitis?
Avoid unnecessary antibiotics, practice good hand hygiene, and maintain a balanced gut microbiome.
What complications arise from untreated pseudomembranous colitis?
Severe dehydration, colonic perforation, or toxic megacolon, which can be life-threatening.
Are there alternative treatments for pseudomembranous colitis?
Fecal microbiota transplantation (FMT) is an option for recurrent or severe cases.
How does pseudomembranous colitis affect the colon?
It causes inflammation and pseudomembrane formation, disrupting normal colon function.
Can children develop pseudomembranous colitis?
Yes, especially after antibiotic use; symptoms and treatment are similar to adults.
What is the role of metronidazole in treatment?
It's effective for mild to moderate cases but not recommended for initial severe episodes.
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