A condition characterized by recurrent kidney stones primarily composed of calcium oxalate, often linked to excess uric acid in urine. This combination increases stone formation risk, requiring targeted treatment.

Calcium Oxalate Calculi with Hyperuricosuria FAQ


What causes calcium oxalate stones with hyperuricosuria?

Excess uric acid in urine promotes calcium oxalate stone formation by reducing the kidney's ability to excrete uric acid, leading to crystal accumulation.

How is hyperuricosuria diagnosed?

Through a 24-hour urine collection test to measure uric acid levels and stone composition analysis.

Can diet affect calcium oxalate stone recurrence?

Yes, reducing oxalate-rich foods (e.g., spinach, nuts) and moderating animal protein intake can help.

What medications lower uric acid levels?

Allopurinol and Febuxostat are commonly prescribed to reduce uric acid production in the body.

Why is potassium citrate prescribed?

It helps increase urine pH, reducing the risk of calcium oxalate stone formation by making urine less acidic.

Is surgery always needed for stone removal?

Not always; small stones may pass naturally with pain management, while larger stones require surgical intervention.

How often should urine tests be conducted?

Regularly, as recommended by your doctor, to monitor uric acid levels and treatment effectiveness.

Can dehydration contribute to stone formation?

Yes, inadequate fluid intake concentrates urine, increasing the likelihood of crystal formation.

Are there specific risks for Malaysians with this condition?

Hot, humid climates may exacerbate dehydration risks, emphasizing the importance of hydration.

How long does stone prevention treatment last?

Typically long-term, as recurrent stones are common without ongoing management.

Can hyperuricosuria be asymptomatic?

Yes, some individuals may not experience symptoms until a stone forms.

What role does family history play?

Genetic predisposition can increase the likelihood of developing this condition, affecting treatment approaches.

Are there alternative treatments available?

While some herbal remedies are suggested, evidence supporting their effectiveness is limited compared to conventional medications.

How does obesity impact this condition?

Excess weight can increase uric acid production and insulin resistance, elevating stone formation risk.

Can medications for this condition cause side effects?

Yes, common side effects include gastrointestinal upset or rash; discuss concerns with your doctor.

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