Chronic Myeloid Leukemia FAQ
What causes CML?
CML is primarily caused by a genetic mutation (Philadelphia chromosome) leading to uncontrolled white blood cell production.
Is CML curable?
CML is often manageable with targeted therapies, but a cure may require a stem cell transplant in eligible patients.
What are common CML symptoms?
Early symptoms may include fatigue, weight loss, night sweats, and enlarged spleen.
How is CML diagnosed?
Diagnosis involves blood tests, bone marrow biopsy, and genetic testing for the Philadelphia chromosome.
What is the main treatment for CML?
Targeted therapy with tyrosine kinase inhibitors (TKIs) like Imatinib is the primary treatment.
Can CML progress to a more severe phase?
Yes, if untreated or resistant to treatment, CML can progress to an accelerated or blast crisis phase.
How often should CML patients follow up?
Regular monitoring every 3-6 months through blood tests and BCR-ABL testing is crucial.
Are there any side effects of CML medication?
Common side effects of TKIs include nausea, diarrhea, and muscle cramps, which are usually manageable.
Can lifestyle changes help manage CML?
Maintaining a healthy diet, staying hydrated, and practicing good hygiene can support overall health.
Is CML contagious?
No, CML is not contagious; it's a genetic disorder and cannot be spread to others.
What is the prognosis for CML patients?
With proper treatment, many CML patients can achieve long-term remission and near-normal life expectancy.
Are there alternative treatments for CML?
Alternative therapies may complement, but not replace, conventional treatments; consult your oncologist.
How does CML affect quality of life?
Effective management can minimize symptoms, allowing many patients to lead active lives.
Can CML be detected early?
Early detection is possible through routine blood tests, even before symptoms appear.
What support resources are available for CML patients in Malaysia?
Patients can seek support from the Malaysian Society of Haematology and Oncology or patient advocacy groups.
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