Chronic Myelogenous Leukemia (CML) is a rare, slow-progressing cancer of the blood and bone marrow characterized by the excessive production of granulocytes. It typically affects adults and is often diagnosed in its chronic phase, where treatment can lead to long-term management.

Chronic Myelogenous Leukemia (CML) FAQ


What causes Chronic Myeloid Leukemia?

CML is primarily caused by a genetic mutation, the Philadelphia chromosome, leading to uncontrolled white blood cell growth.

Is CML hereditary?

No, CML is not typically inherited; it develops due to acquired genetic changes.

What are common CML symptoms?

Fatigue, weight loss, night sweats, and an enlarged spleen are common symptoms.

How is CML diagnosed?

Diagnosis involves blood tests, bone marrow biopsy, and genetic testing for the BCR-ABL gene.

What is the primary treatment for CML?

Targeted therapy with tyrosine kinase inhibitors (TKIs) like Imatinib is the first-line treatment.

Can CML be cured?

While not always curable, TKIs can induce long-term remission, managing the disease effectively.

How often are treatment appointments needed?

Regular monitoring (every 3-6 months) through blood tests and physician consultations is crucial.

Can diet influence CML management?

A balanced diet supports overall health but does not directly impact CML treatment efficacy.

Are there alternative therapies for CML?

No proven alternative therapies; adherence to prescribed TKIs is essential for disease control.

What if I experience side effects from medication?

Consult your doctor for dosage adjustments or alternative medications to manage side effects.

Is stem cell transplant an option for CML?

Reserved for specific cases, such as TKI resistance or disease progression.

Can I travel with CML?

Yes, but ensure access to medication and medical care during travel.

How does CML affect daily life?

With proper management, many individuals lead active lives, though regular medical visits are necessary.

What if I miss a dose of medication?

Take the missed dose as soon as remembered, but avoid doubling up doses.

Are there clinical trials for CML in Malaysia?

Check with local oncology centers or the Malaysian Ministry of Health for available trials.

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