Sickle cell anemia is a genetic blood disorder caused by abnormal hemoglobin, leading to misshapen red blood cells. These 'sickle' cells can block blood flow, causing pain, anemia, and increased infection risk, requiring lifelong management.

Sickle Cell Anemia FAQ


What causes sickle cell anemia?

It's caused by a genetic mutation affecting hemoglobin production, inherited from both parents.

Is sickle cell anemia common in Malaysia?

It's relatively rare in Malaysia but can affect individuals of African, Mediterranean, or Middle Eastern descent.

What are common symptoms of sickle cell anemia?

Pain episodes, fatigue, pale skin, shortness of breath, and increased infections.

How is sickle cell anemia diagnosed?

Through blood tests, including hemoglobin electrophoresis, and genetic testing.

Can sickle cell anemia be cured?

Currently, the only potential cure is a bone marrow transplant, which isn't always feasible.

What medications help manage sickle cell anemia?

Hydroxyurea reduces pain episodes, while pain relievers and supplements address symptoms.

How often do pain crises occur?

Frequency varies; some experience frequent episodes, while others may have few or none.

Can a healthy lifestyle help manage sickle cell anemia?

Yes, staying hydrated, avoiding extreme temperatures, and regular exercise can help.

Are there support groups for sickle cell anemia in Malaysia?

Yes, organizations like the Malaysian Thalassaemia and Sickle Cell Society offer support.

Can sickle cell anemia be passed to children?

Yes, if both parents carry the sickle cell trait, there's a 25% chance per child.

How is sickle cell trait different from sickle cell anemia?

The trait is a mild form with no symptoms, while anemia is the severe, symptomatic form.

Pneumococcal, influenza, and meningococcal vaccines to prevent infections.

Can sickle cell anemia affect life expectancy?

With proper care, many live into adulthood, though life expectancy may be reduced.

How is sickle cell anemia managed in Malaysia?

Through a multidisciplinary approach, including hematologists, pain management, and regular blood transfusions.

Are there clinical trials for sickle cell anemia treatments in Malaysia?

Yes, though availability may be limited; consulting a hematologist is advised.

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