Chlorambucil is a chemotherapy medication used to treat certain cancers, including chronic lymphocytic leukemia and non-Hodgkin's lymphoma. It belongs to the alkylating agent class, working by interfering with cancer cell DNA replication. Available in oral form, it requires careful dosing and monitoring due to potential side effects.

Chlorambucil FAQ


What is Chlorambucil used for?

It treats chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and other cancers.

How does Chlorambucil work?

It damages cancer cell DNA, preventing replication and slowing tumor growth.

What are common side effects of Chlorambucil?

Nausea, vomiting, fatigue, and increased infection risk due to low blood counts.

Is Chlorambucil taken orally?

Yes, it is typically administered in tablet form.

How often is Chlorambucil taken?

Dosing varies, but often daily for a set period, followed by breaks.

Does Chlorambucil cause hair loss?

Less commonly than other chemotherapies, but possible in some cases.

Can Chlorambucil affect fertility?

Yes, it may impact fertility in both men and women.

What medications interact with Chlorambucil?

Other chemotherapy drugs, immunosuppressants, and certain antibiotics.

How is Chlorambucil dosed?

Based on body weight, kidney function, and treatment response.

Is Chlorambucil used for conditions other than cancer?

Sometimes for severe autoimmune diseases, though not common.

Can Chlorambucil be taken with food?

Yes, to help reduce stomach upset.

What are signs of Chlorambucil overdose?

Severe nausea, vomiting, and bone marrow suppression.

How long does Chlorambucil treatment last?

Varies by individual response and cancer type.

Does Chlorambucil require regular blood tests?

Yes, to monitor blood cell counts and liver/kidney function.

Is Chlorambucil available in Malaysian pharmacies?

Yes, typically through specialist oncology prescriptions.

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